Introduction:

Many epidemiological studies support the protective role of garlic and related allium foods against the development of certain human cancers. Natural garlic and garlic cultivated with selenium fertilization have been shown in laboratory animals to have protective roles in cancer prevention. Certain organoselenium compounds and their sulfur analogs have been identified in plants.
Garlic (Allium sativum) is known to significantly affect human health. As early as 1550 B.C., Egyptians had realized the effects of garlic as a remedy for a variety of diseases . The health benefits of garlic appear to be true today .Several epidemiological studies suggest that consumption of garlic and related allium foods reduces the risk of certain cancer types, including those of the gastro-intestinal tract .Two independent reports showed a reduced risk of prostate cancer with an increased intake of garlic.

Preclinical investigations provide convincing evidence that garlic and related sulfur-containing compounds inhibit carcinogen-induced tumors in various organs . As early as 1958, Weisberger and Pensky demonstrated an antiproliferative action of garlic, and follow-up studies further documented the protective effects of garlic against the development of a number of cancers . Consumption of garlic and related sulfur compounds by laboratory animals reduced carcinogeninduced mammary, colon, esophageal, lung, forestomach, skin, and liver tumors .

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