Resveratrol

Plant source          :Polygonum cuspidatum

Specification         :50%, 98%,99%
                                   Water-soluble resveratrol 5%, 10%

                                   Acetyl-resveratrol 98%
                                   Micronized resveratrol 98%

Appearence           :Brownish yellow powder/White powder

M.W                          :228.246/M.F  :C14H12O3

Introduction  :

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi.

The effects of resveratrol are currently a topic of numerous animal and human studies. Its effects on the lifespan of many model organisms remain controversial, with uncertain effects in fruit flies, nematode worms, and short-lived fish. In mouse and rat experiments, anticancer, anti-inflammatory, blood sugar-lowering and other beneficial cardiovascular effects of resveratrol have been reported. These results have yet to be replicated in humans.

In the only positive human trial, extremely high doses (3–5 g) of resveratrol, in a proprietary formulation designed to enhance its bioavailability, significantly lowered blood sugar.This 28-day Phase 1b study was conducted privately in India by pharmaceutical company Sirtris, and was announced in an investors conference in 2008. However, although it has been alluded to in review articles, the study itself has never been published in a peer-reviewed scientific publication. Despite mainstream press alleging resveratrol's anti-aging effects,there are no accepted data to form a scientific basis for the application of these claims to mammals.

Resveratrol is found in the skin of red grapes and in other fruits. However, red wine contains very little of it, on the order of one milligram a glass, and no reputable scientists believe it is the factor behind the French paradox. Most believe proanthocyanidin is the active ingredient involved. Resveratrol has also been produced by chemical synthesis or by biotechnological synthesis (metabolic engineered microorganisms) and is sold as a nutritional supplement derived primarily from Japanese knotweed.

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